1. Blade, Ghost Rider & Spider-Man (Stark Enhanced)

⚡ Spirit of Justice – (Blade with Ghost Rider)
➥ Blade : expands his Danger Sense bonuses to include all Villain Champions
➥ Ghost Rider : gets a +50% chance to place a Judgement
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Heightened Senses – (Blade with Spider-Man Stark Enhanced)
➥ Blade : delivers +45% Potency for Danger Sense bonuses.
➥ Spider-Man (Stark Enhanced) : gets to start the fight with 3 Poise charges.
➥ Unique Synergy : Does not stack with duplicate synergies.

2. Corvus Glaive, Proxima Midnight & Nebula

⚡ Challenge Defenses – (Corvus Glaive with Proxima Midnight)
➥ Corvus Glaive : Use a Heavy or Special Attack to knock down an opponent that used Evade or Auto-Block in a fight. Once this mission is complete, his True Damage becomes True Strike.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Infinity Enemies – (Corvus Glaive with Nebula)
➥ All Champions : gain +7% Attack
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Unmerciful Punishment – (Proxima Midnight with Nebula)
➥ Proxima Midnight : When True Accuracy is active, her Attack Rating is increased by 15%.
➥ Nebula : Starts the fight with 10 Electroshock Charges.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Special Assist – (Proxima Midnight with Corvus Glaive)
➥ Proxima Midnight : Ultimate Mission’s Combo Meter requirement goes down to 75 hits.
➥ Unique Synergy : Does not stack with duplicate synergies.

3. Ghost, Wasp & Ant Man

⚡ Formidable Foe – (Ghost with Ant Man)
➥ Ghost : +15% Attack for each Buff on Ghost.
➥ Ant Man : +15% Attack for each Debuff on opponent.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Microscopic Observation – (Ghost with Wasp)
➥ Ghost : Special Attack are Unblockable when triggered while Phasing.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Hard TO Hit – (Wasp, Ant Man and Ghost)
➥ Wasp : Counter sting is never disabled when Wasp is below 20% Health.
➥ Ant Man : When Glancing Hits, he gain 25% increased attack for 12 seconds.
➥ Wasp, Ant Man and Ghost : +25% Attack at the start of the fight if Wasp, Ant Man and Ghost are together in a team.
➥ Unique Synergy : Does not stack with duplicate synergies.

4. Sabretooth, Killmonger & Winter Soldier

⚡ No Mercy – (Sabretooth with Killmonger)
➥ Sabretooth : Inflicting a Debuff reduces the opponents Ability Accuricy by 100% for 0.7 seconds.
➥ Black Panthers, Killmonger : +30% Power Rate when hitting opponents that are suffering from a Debuff.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Enhanced Soldiers Lv.3 – (Killmonger with Winter Soldier)
➥ Killmonger : 100% chance to activate True Strike when intercepting the opponents Dash
➥ Winter Soldier : +5% Attack for each hit of the Combo Meter to maximum of 100 hits
➥ Unique Synergy : Does not stack with duplicate synergies.

5. Domino, Red Hulk & Masacre

⚡ Mercs For Money – (Masacre with Domino)
➥ Masacre : At the start of the fight, and when Ignited expires, gain between 1 and 5 Ignition Charges.
➥ Domino : Debuff last 1 seconds longer.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Playing with Fire – (Masacre with Red Hulk)
➥ Masacre : Blocking a contact attack while Ignited places an Incinerate on the Opponent as if they had been struck by Masacre’s bat.
➥ Red Hulk : Start the fight with 2 Heat Charges.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Code Red Revelations – (Domino with Red Hulk)
➥ Domino : Heavy Attacks inflict an Incinerate that deals damage equal to that Heavy Attack’s damage over 2 seconds.
➥ Red Hulk : Special 2 Regeneration consumes 1 less Heat Charge and recovers 18% more Health.
➥ Unique Synergy : Does not stack with duplicate synergies.

6. Void, Killmonger & Sabretooth

⚡ Fearless – (Killmonger with Void)
➥ Killmonger : If Vibranium Armor is active, Killmonger has a 35% chance to Purify a Debuff after a 0.5 second delay and
then instantly Regenerate 4% Health per Debuff.
➥ Void : Regenerates 1% Health when inflicting his Intimidating Debuffs.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ No Mercy – (Sabretooth with Killmonger)
➥ Sabretooth : Inflicting a Debuff reduces the opponent’s Ability Accuracy by 100% for 0.7 seconds.
➥ Black Panthers, Killmonger : +30% Power Rate when hitting opponents suffering from a Debuff.
➥ Unique Synergy : Does not stack with duplicate synergies.

7. Void, Hulk & Thor

⚡ Enemies Level 3 – (Void with Thor)
➥ All Champions : gain +155 Critical Rating.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Gripped by Fear – (Void with Hulk)
➥ Void : When charging Heavy Attacks, Void can gain up to 3 Fury Buffs, each enhancing his Attack Rating by 20% for 8
seconds.
➥ Hulk : Gains 1 bar of Power when below 20% Health.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Rivals Level 3 – (Hulk with Thor)
➥ All Champions : gain +115 Critical Damage Rating.
➥ Unique Synergy : Does not stack with duplicate synergies.

8. Ghost, Wasp & The Hood

⚡ Microscopic Observation (Ghost with Wasp)
➥ Ghost : Special Attacks are Unblockable when triggered while Phasing
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Enemies level 3 (Wasp with Hood)
➥ All Champions : gain +155 Critical Rating
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ The Untouchables (Ghost with Hood)
➥ Ghost: Take no damage while Phasing.
➥ The Hood: Start the fight Invisible
➥ Unique Synergy: Does not stack with duplicate synergies.