Credit: Seatin Man of Legends

★ = Large benefit from Awakened Ability
💪 = Large benefit from High Signature Level
💑 = Large benefit from Synergies
⬆️ = Needs fights to Ramp Up
🤸🏻‍♂️= High Skill Required
💀 = Large Benefit From Suicides

Beyond God Tier (SS)

Colossus ★💪💑
Domino 💑💀
Omega Red ★💪💑💀
Namor ★💪💀
Archangel ★
Sunspot
Doctor Doom
Aegon ★💪⬆️💀
Nick Fury ★🤸🏻‍♂️
Corvus Glaive ⬆️💀
Hyperion ★
Captain Marvel Movie ★💑💀
Ghost 💑🤸🏻‍♂️💀
Warlock 💀
Guillotine 2099 🤸🏻‍♂️⬆️
Void ★💪
Captain America (IW) ★💪💑
Quake 🤸🏻‍♂️💀
Human Torch 💑
Thing 💑🤸🏻‍♂️

Solid God Tier (S)

Havok
Wolverine Weapon X
Sabretooth 💑⬆️
Symbiote Supreme
Longshot
Black Widow (Claire V)💀
Sorcerer Supreme
Magik 🤸🏻‍♂️💀
Spider-Man Stealth
Blade ★💑
Hit Monkey 💀
Medusa ★💑
Venom
Venom The Duck ⬆️
Cull Obsidian ★💪⬆️
Spider-Man (Stark) ★
Sentinel ★💀
Guardian ★💪💀
Hulkbuster ★🤸🏻‍♂️
She Hulk 🤸🏻‍♂️
Red Guardian ★💪

God Tier (A)

Iceman 💀
Emma Frost 💀
Wolverine ★
Ghost Rider ★💀
Doctor Voodoo ★🤸🏻‍♂️
Morningstar ⬆️💀
Mojo ★💪
Scarlet Witch ★💪
Tigra ★💪🤸🏻‍♂️
Sasquatch
Gwenpool ★
Night Thrasher ★💪💑
Black Widow Movie
Killmonger ★💪
Proxima Midnight ★🤸🏻‍♂️
Vision (Aarkus)
Silver Surfer ★💪🤸🏻‍♂️
Star-Lord ★
Darkhawk ★💪💑💀
Iron Man (IW) ★🤸🏻‍♂️💑
Doctor Octopus ★🤸🏻‍♂️
Gladiator Hulk
Luke Cage 💑

High Demi-God Tier (B)

Wolverine X-23
Mister Sinister ★💪
Old Man Logan ★💪
Storm (Pyramid X)
Mephisto 💑💀
Masacre 💑
Ronin 🤸🏻‍♂️💀
Winter Soldier 💑
Elsa Bloodstone
Squirrel Girl
Carnage
Hela 💑🤸🏻‍♂️
Thor ★
Angela
Kamala Khan ★💑
Gamora 💑
Vision (Both) ★💀
Mysterio
Mister Fantastic ★💪💑
Wasp 💑🤸🏻‍♂️
Red Hulk
Spider-Gwen 💑
Hulk ★💑
Invisible Woman 🤸🏻‍♂️

Low Demi-God Tier (C)

Rogue
Bishop
Psylocke ★
Dormammu 💀
The Hood
Guillotine
Man-Thing
Mordo
Taskmaster ★💪🤸🏻‍♂️
Crossbones
Black Widow OG ★💪
Hawkeye
Thor (Ragnarok) ★💪💑
Mole Man ★💪💀
Black Bolt ★💪💑
The Champion
Heimdall
Annihilus 💑
Terrax ★💪
Ronan ★
Nova ★💪
Nebula 💑
M.O.D.O.K
Sentry ★⬆️💑

Useful Tier (D)

Storm ★
Cable
Nightcrawler
Beast ★
Goldpool
Loki
Elektra
Daredevil (Classic) ★💪
Korg
Ms. Marvel ★
Captain Marvel ★
Phoenix
Drax
Spider-Man Symbiote
Yondu
Punisher 2099
Red Skull
Rocket Raccoon
Kang
Ultron 💀
Captain America WW2
Yellow Jacket
Electro ★
Ant-Man ★💑

Occasionally Useful Tier (E)

Cyclops (Both) ★
Gambit
Magneto (Both)
Thor (Jane Foster) ★
Iron Fist ★
Dr. Strange ★💑
Diablo ★💑
Ebony Maw
Punisher
Black Panther (Classic) ★
Kingpin
Agent Venom
Black Panther (Civil War) 💑
Karnak
King Groot ★
Thanos
Green Goblin
Civil Warrior
Vulture
Howard The Duck
Captain America (Classic)
Spiderman (Classic)

Meme Tier (F)

Deadpool X-Force ★
Unstoppable Colossus
Juggernaut
Falcon
Daredevil (Netflix)
Moon Knight
Superior Iron Man ★
Venompool
Groot
Iron Man ★
War Machine
Iron Patriot
Spider-Man Miles Morales
Rhino
Joe Fixit
Abomination

1. Blade, Ghost Rider & Spider-Man (Stark Enhanced)

⚡ Spirit of Justice – (Blade with Ghost Rider)
➥ Blade : expands his Danger Sense bonuses to include all Villain Champions
➥ Ghost Rider : gets a +50% chance to place a Judgement
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Heightened Senses – (Blade with Spider-Man Stark Enhanced)
➥ Blade : delivers +45% Potency for Danger Sense bonuses.
➥ Spider-Man (Stark Enhanced) : gets to start the fight with 3 Poise charges.
➥ Unique Synergy : Does not stack with duplicate synergies.

 
2. Corvus Glaive, Proxima Midnight & Nebula

⚡ Challenge Defenses – (Corvus Glaive with Proxima Midnight)
➥ Corvus Glaive : Use a Heavy or Special Attack to knock down an opponent that used Evade or Auto-Block in a fight. Once this mission is complete, his True Damage becomes True Strike.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Infinity Enemies – (Corvus Glaive with Nebula)
➥ All Champions : gain +7% Attack
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Unmerciful Punishment – (Proxima Midnight with Nebula)
➥ Proxima Midnight : When True Accuracy is active, her Attack Rating is increased by 15%.
➥ Nebula : Starts the fight with 10 Electroshock Charges.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Special Assist – (Proxima Midnight with Corvus Glaive)
➥ Proxima Midnight : Ultimate Mission’s Combo Meter requirement goes down to 75 hits.
➥ Unique Synergy : Does not stack with duplicate synergies.

 
3. Ghost, Wasp & Ant Man

⚡ Formidable Foe – (Ghost with Ant Man)
➥ Ghost : +15% Attack for each Buff on Ghost.
➥ Ant Man : +15% Attack for each Debuff on opponent.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Microscopic Observation – (Ghost with Wasp)
➥ Ghost : Special Attack are Unblockable when triggered while Phasing.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Hard TO Hit – (Wasp, Ant Man and Ghost)
➥ Wasp : Counter sting is never disabled when Wasp is below 20% Health.
➥ Ant Man : When Glancing Hits, he gain 25% increased attack for 12 seconds.
➥ Wasp, Ant Man and Ghost : +25% Attack at the start of the fight if Wasp, Ant Man and Ghost are together in a team.
➥ Unique Synergy : Does not stack with duplicate synergies.

 
4. Sabretooth, Killmonger & Winter Soldier

⚡ No Mercy – (Sabretooth with Killmonger)
➥ Sabretooth : Inflicting a Debuff reduces the opponents Ability Accuricy by 100% for 0.7 seconds.
➥ Black Panthers, Killmonger : +30% Power Rate when hitting opponents that are suffering from a Debuff.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Enhanced Soldiers Lv.3 – (Killmonger with Winter Soldier)
➥ Killmonger : 100% chance to activate True Strike when intercepting the opponents Dash
➥ Winter Soldier : +5% Attack for each hit of the Combo Meter to maximum of 100 hits
➥ Unique Synergy : Does not stack with duplicate synergies.

 
5. Domino, Red Hulk & Masacre

⚡ Mercs For Money – (Masacre with Domino)
➥ Masacre : At the start of the fight, and when Ignited expires, gain between 1 and 5 Ignition Charges.
➥ Domino : Debuff last 1 seconds longer.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Playing with Fire – (Masacre with Red Hulk)
➥ Masacre : Blocking a contact attack while Ignited places an Incinerate on the Opponent as if they had been struck by Masacre’s bat.
➥ Red Hulk : Start the fight with 2 Heat Charges.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Code Red Revelations – (Domino with Red Hulk)
➥ Domino : Heavy Attacks inflict an Incinerate that deals damage equal to that Heavy Attack’s damage over 2 seconds.
➥ Red Hulk : Special 2 Regeneration consumes 1 less Heat Charge and recovers 18% more Health.
➥ Unique Synergy : Does not stack with duplicate synergies.

 
6. Void, Killmonger & Sabretooth

⚡ Fearless – (Killmonger with Void)
➥ Killmonger : If Vibranium Armor is active, Killmonger has a 35% chance to Purify a Debuff after a 0.5 second delay and
then instantly Regenerate 4% Health per Debuff.
➥ Void : Regenerates 1% Health when inflicting his Intimidating Debuffs.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ No Mercy – (Sabretooth with Killmonger)
➥ Sabretooth : Inflicting a Debuff reduces the opponent’s Ability Accuracy by 100% for 0.7 seconds.
➥ Black Panthers, Killmonger : +30% Power Rate when hitting opponents suffering from a Debuff.
➥ Unique Synergy : Does not stack with duplicate synergies.

 
7. Void, Hulk & Thor

⚡ Enemies Level 3 – (Void with Thor)
➥ All Champions : gain +155 Critical Rating.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Gripped by Fear – (Void with Hulk)
➥ Void : When charging Heavy Attacks, Void can gain up to 3 Fury Buffs, each enhancing his Attack Rating by 20% for 8
seconds.
➥ Hulk : Gains 1 bar of Power when below 20% Health.
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Rivals Level 3 – (Hulk with Thor)
➥ All Champions : gain +115 Critical Damage Rating.
➥ Unique Synergy : Does not stack with duplicate synergies.

 
8. Ghost, Wasp & The Hood

⚡ Microscopic Observation (Ghost with Wasp)
➥ Ghost : Special Attacks are Unblockable when triggered while Phasing
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ Enemies level 3 (Wasp with Hood)
➥ All Champions : gain +155 Critical Rating
➥ Unique Synergy : Does not stack with duplicate synergies.

⚡ The Untouchables (Ghost with Hood)
➥ Ghost: Take no damage while Phasing.
➥ The Hood: Start the fight Invisible
➥ Unique Synergy: Does not stack with duplicate synergies.

Captain Marvel Cosmic Sep-05 Sept-09
Hela Cosmic Sep-12 Sept-16
Nick Fury Skill Sep-19 Sep-23
Captain America IW Science Sep-26 Sep-30
Annihilus Cosmic Oct-03 Oct-07
Spidey Classic Science Oct-10 Oct-14
Human Torch Science Oct-17 Oct-21
Star-Lord Tech Oct-24 Oct-28
Ronin Skill Oct-31 Nov-04
Proxima Midnight Cosmic Nov-07 Nov-11
Cull Obsidian Cosmic Nov-14 Nov-18
Iron Man IW Tech Nov-21 Nov-25
Ebony Maw Mystic Nov-28 Dec-02
Dr. Strange Mystic Dec-05 Dec-09
Namor Mutant Dec-12 Dec-16
Not Known NA
Invisible Woman Science Dec-26 Dec-30
2015 Champions
Champions
Class
Colossus Mutant
Cyclops (Red) Mutant
Deadpool Mutant
Deadpool (X-Force) Mutant
Magneto (red) Mutant
Magneto (white) Mutant
Storm Mutant
Wolverine* Mutant
Dr. Strange Mystic
Guillotine Mystic
Iron Fist Mystic
Juggernaut Mystic
Magik Mystic
Scarlet Witch* Mystic
Thor (Jane Foster) Mystic
Unst. Colossus Mystic
Black Panther Skill
Black Widow Skill
Daredevil Skill
Daredevil (Classic) Skill
Elektra Skill
Hawkeye Skill
Moon Knight Skill
Punisher Skill
Winter Soldier Skill
Black Bolt Cosmic
Drax Cosmic
Gamora Cosmic
Groot Cosmic
Ms. Marvel Cosmic
Ronan Cosmic
Spiderman (Symbiote) Cosmic
Superior Iron-Man Cosmic
Thor Cosmic
Venom Cosmic
Hulkbuster Tech
Iron Patriot Tech
Iron-Man Tech
Kang Tech
Rocket Raccoon Tech
Star-Lord Tech
Ultron Tech
Vision (Age of Ultron)* Tech
Vision (Classic) Tech
War Machine Tech
Abomination Science
Ant-Man Science
Captain America Science
Captain America (WWII) Science
Electro Science
Hulk Science
Joe Fixit Science
Luke Cage Science
Rhino Science
Spider Gwen Science
Spiderman (Classic) Science
Yellowjacket Science
2016 Champions
Champions
Class
Rogue Mutant
Wolverine X-23 Mutant
Beast Mutant
Nightcrawler Mutant
Cyclops (Blue Team) Mutant
Gambit Mutant
Old-Man Logan Mutant
Doctor Voodoo Mystic
Ghost Rider Mystic
Loki Mystic
Mordo Mystic
Agent venom Skill
Karnak Skill
Crossbones Skill
Falcon Skill
Black Panther (CW) Skill
Kamala Khan Cosmic
Phoenix Cosmic
Thanos Cosmic
Hyperion Cosmic
Venompool Cosmic
Civil Warrior Tech
Howard the Duck Tech
Ultron (Classic) Tech
Quake Science
She-Hulk Science
Red Hulk Science
Spiderman (Miles Morales) Science
2017 Champions
Champions
Class
Cable Mutant
Psylocke Mutant
Archangel Mutant
Iceman Mutant
Dormammu Mystic
Mephisto Mystic
Morningstar Mystic
The Hood Mystic
Kingpin Skill
Taskmaster Skill
Blade Skill
Gwenpool Skill
Thor Ragnarok Skill
Angela Cosmic
Hela Cosmic
Carnage Cosmic
King Groot Cosmic
Medusa Cosmic
Vulture Tech
Green Goblin Tech
Punisher 2099 Tech
Yondu Tech
Doctor Octopus Tech
Nebula Tech
Spiderman (Stark) Tech
MODOK Science
2018 Champions
Champions
Class
Omega Red Mutant
Sabretooth Mutant
Bishop Mutant
Domino Mutant
Goldpool Mutant
Emma Frost Mutant
Symbiote Supreme Mystic
Ægon Skill
Korg Skill
Masacre Skill
Killmonger Skill
Night Thrasher Skill
Corvus Glaive Cosmic
Proxima Midnight Cosmic
The Champions Cosmic
Heimdall Cosmic
Venom the Duck Cosmic
Ghost Tech
iron Man IW Tech
Sentinel Tech
Red Skull Tech
Hulk Ragnarok Science
Void Science
Wasp Science
Captain America (IW) Science
Sentry Science
2019 Champions
Champions
Class
Namor Mutant
Havok Mutant
Mister Sinister Mutant
Sunspot Mutant
Diablo Mystic
Ebony Maw Mystic
Black Widow (Claire Voyant) Mystic
Ronin Skill
Spiderman (Stealth Suit) Skill
Nick Fury Skill
Annihilus Cosmic
Captain Marvel Cosmic
Cull Obsidian Cosmic
Vision (Aarkus) Cosmic
Mysterio Tech
Warlock Tech
Human Torch Science
Thing Science
Invisible Woman Science
Rank
Champions
Prestige
1 Thor Ragnarok 11564
2 Namor 11555
3 Phoenix 11540
4 Captain Marvel 11510
5 Diablo 11470
6 Thing 11469
7 The Champion 11462
8 Havok 11414
9 Symbiote Supreme 11407
10 Nick Fury 11401
11 Human Torch 11393
12 Sabretooth 11388
13 Sentry 11387
14 Korg 11386
15 Invisible Woman 11372
16 Ebony Maw 11371
17 Corvus Glaive 11349
18 Annihilus 11341
19 Wasp 11323
20 Ægon 11322
21 Mister Sinister 11317
22 Cull Obsidian 11316
23 Proxima Midnight 11301
24 Sentinel 11297
25 Emma Frost 11285
26 M.O.D.O.K 11274
27 Darkhawk 11265
28 Mephisto 11265
29 Bishop 11262
30 Green Goblin 11255
31 Ronin 11223
32 Killmonger 11211
33 Night Thrasher 11189
34 Heimdall 11187
35 Red Skull 11184
36 Punisher 2099 11167
37 Captain America IW 11150
38 Masacre 11148
39 Mordo 11126
40 Loki 11117
41 Iron Man IW 11103
42 Void 11100
43 Hela 11078
44 Carnage 11066
45 The Hood 11039
46 Omega Red 10992
47 Vulture 10928
48 Cable 10906
49 Gamora 10903
50 Psylocke 10900
51 Ghost 10891
52 Civil Warrior 10886
53 Domino 10875
54 Doctor Octopus 10859
55 Kingpin 10811
56 Angela 10783
57 Dr. Strange 10782
58 Beast 10771
59 Iron Fist 10740
60 Morningstar 10740
61 Red Hulk 10703
62 Ultron 10694
63 Black Panther CW 10677
64 Venom the Duck 10666
65 King Groot 10632
66 Luke Cage 10613
67 Hulk Ragnarok 9785
68 Yondu 10582
69 Hulkbuster 10567
70 Thor (Jane Foster) 10538
71 Nebula 10529
72 Dormammu 10459
73 Deadpool (X-Force) 10347
74 Guillotine 10311
75 Electra 10289
76 Rocket Raccoon 10284
77 Yellowjacket 10190
78 Daredevil (Classic) 10158
79 Cyclops (Blue Team) 10142
80 Electro 10125
81 Magneto 10099
82 Spider-Man (Miles) 10092
83 Storm 10055
84 Karnak 9968
85 Drax 9897
86 Captain Marvel (Classic) 9817
87 Black Bolt 9779
88 Winter Soldier 9743
89 Spider-Man (Classic) 9740
90 Juggernaut 9734
91 Nightcrawler 9666
92 Captain America (WWII) 9646
93 Gambit 9646
94 Rhino 9603
95 Hawkeye 9571
96 Ant-Man 9522
97 Iron Fist 9417
98 Cyclops (New Xavier School) 9102
99 Moon Knight 8775
Stats are based on Rank 5 Maxed Out Champions (200 Signatures)
Rank
Champions
Prestige
1 Thor Ragnarok 10690
2 Namor 10670
3 Phoenix 10650
3 Goldpool 10650
4 Spider-Man (Stealth Suit) 10640
5 Captain Marvel 10630
5 Sunspot 10630
6 Warlock 10620
6 Black Widow (Claire Voyant) 10620
7 Thing 10600
7 Diablo 10600
8 The Champion 10590
9 Vision (Aarkus) 10580
10 Mysterio 10550
11 Havok 10550
12 Symbiote Supreme 10540
13 Human Torch 10530
14 Sentry 10530
15 Korg 10520
16 Sabretooth 10510
17 Invisible Woman 10510
18 Ebony Maw 10500
19 Annihulus 10480
20 Corvus Glaive 10480
21 Thanos 10470
22 Nick Fury 10470
23 Mister Sinister 10460
24 Ægon 10460
25 Wasp 10460
26 Cull Obsidian 10450
27 Blade 10450
28 Sentinel 10450
29 Ghost Rider 10440
30 Proxima Midnight 10440
31 Emma Frost 10430
32 M.O.D.O.K 10420
33 Mephisto 10420
34 Doctor Voodoo 10410
35 Bishop 10410
36 Darkhawk 10410
37 Green Goblin 10400
38 Gwenpool 10400
39 Ronin 10390
40 Quake 10380
41 Killmonger 10370
42 Red Skull 10350
43 Heimdall 10340
44 Punisher 2099 10330
45 Captain America IW 10300
46 Masacre 10300
47 Mordo 10280
48 Loki 10270
49 Iron Man Infinity War 10260
50 Void 10260
51 Hela 10230
52 Carnage 10220
53 Rogue 10210
54 The Hood 10210
55 Taskmaster 10200
56 Omega Red 10160
57 Night Thrasher 10160
58 Vulture 10100
59 Cable 10080
60 Civil Warrior 10070
61 Ghost 10070
62 Psylocke 10070
63 Archangel 10060
64 Domino 10050
65 Doctor Octopus 10040
66 Iron Fist 10030
67 Black Panther (CW) 10010
68 Magik 10010
69 Vision 10000
70 Kingpin 9990
71 Dr. Strange 9970
72 Angela 9960
73 Beast 9960
74 Morningstar 9930
75 Agent Venom 9920
76 Red Hulk 9900
77 Medusa 9890
78 Ultron 9890
79 Spider-Gwen 9870
80 Venom The Duck 9860
81 King Groot 9850
82 Falcon 9830
83 Iceman 9820
84 Luke Cage 9820
85 Hyperion 9810
86 Hulk Ragnarok 9780
87 Yondu 9780
88 Thor (Classic) 9780
89 Hulkbuster 9770
90 Thor (Jane Foster) 9740
91 Venom 9740
92 Nebula 9730
93 Superior Iron Man 9690
94 Dormammu 9680
95 Kang 9670
96 Venompool 9560
97 Black Widow 9550
98 Ms. Marvel 9540
99 Guillotine 9530
100 Electra 9500
101 Rocket Raccoon 9490
102 Groot 9470
103 Spider-Man (Stark) 9470
104 Yellow Jacket 9420
105 Daredevil (Classic) 9390
106 Ultron (Classic) 9380
107 Cyclops (Blue Team) 9370
108 Electro 9340
109 Daredevil (Netflix) 9340
110 Magneto 9330
111 Spider-man (Miles) 9320
112 Iron Patriot 9320
113 Old Man Logan 9310
114 Colossus 9290
115 Storm 9290
116 Abomination 9210
117 Karnak 9210
118 Hulk 9200
119 Captain America 9170
120 Spider-Man (Symbiote) 9170
121 Drax 9140
122 Punisher 9130
123 Captain Marvel (Classic) 9070
124 Black Bolt 9030
125 Winter Soldier 9010
126 Juggernaut 9000
127 Spiderman (classic) 8990
128 Unst. Colossus 8990
129 Star-Lord 8980
130 Howard the Duck 8970
131 Ronan 8970
132 Nightcrawler 8930
133 Gambit 8910
134 Rhino 8880
135 Hawkeye 8840
136 Black Panther (Classic) 8830
137 Ant-Man 8810
138 Iron Fist 8690
139 She-Hulk 8680
140 Crossbones 8680
141 Wolverine X-23 8490
142 Cyclops (New Xavier School) 8410
143 Moon Knight 8120
144 Iron Man (Classic) 8090
Champions
Immunity
Omega Red Poison
Iceman Bleed + Poison + Incinerate
Havok Incinerate
Sunspot Incinerate
Mister Sinister Mind Control + Taunt
Sabretooth Coldsnap + Frostbite
Magneto (Both) Mind Control
Colossus Bleed
Ghost Rider Bleed
Morningstar Bleed
Mephisto Poison + Coldsnap + Frostbite
Dormammu Bleed + Poison
Unstoppable Colossus Bleed + Mind Control
Juggernaut Mind Control
Night Thrasher Incinerate
Korg Bleed + Shock
Hyperion Poison
Medusa Poison
Captain Marvel Movie Poison
Kamala Khan Poison
Ms. Marvel Poison
Captain Marvel Poison
Ronan Poison
Black Bolt Poison
King Groot Bleed
Groot Bleed
Darkhawk Bleed + Poison
Sentinel Bleed + Poison
Warlock Bleed + Poison + Coldsnap + Frostbite
Vision (Both Versions) Bleed + Poison
Mysterio Poison
Ultron (Both Versions) Bleed + Poison
Nebula Bleed + Poison
Vulture (Duped) Incinerate
Void Incinerate
Thing Bleed + Shock + Armor Break/Shatter + Nullify + Stagger + Fate Seal
Gladiator Hulk Poison
She Hulk Poison
Luke Cage Bleed
Red Hulk Incinerate
Human Torch Incinerate
Hulk Poison
Electro Shock
Joe Fixit Poison
Abomination Poison
Conditional Immunity and Champs that Shurg-off Debuffs
Champions
Immunity
Omega Red 90% reduced bleed damage
Emma Frost Everything(in Diamond Form).
Not Immune to Mind-Control
Mister Sinister No Immunity but the first special attack will transfer all the debuffs to the opponent. So he is usable for Bleed, Poison or any debuff node Node.
Rogue 70% Reduced Duration for all Debuffs
Bishop Shrug off 1 bleed stack at the cost of 1 prowess charge
Cable Each successive poison duration reduced by 20% until he becomes fully immune
Beast 65% reduced bleed damage
Old-Man Logan 85% reduced bleed damage
Blade 85% chance to prevent debuffs from triggering againstall Villians character. Keep his Power Meter Full to make him shrug off debuff from all characters including heroes. Add Ghost Rider in Team to Prevent Debuffs from All Mystic Champs (even heroes)
Ægon (Duped) Up to 100% immune (Depends on Combo Meter)
Killmonger with Void Synergy KIllmonger has a 35% chance to purify a debuff and regenerate 4% health when Vibranium Armor is active.
Taskmaster Each successive debuff reduces potency by 10%, until 10 when he becomes fully immune.
Crossbones 25% Chance to Shrug off all debuffs
Kingpin 50% Chance to Shrug off all debuffs
Agent Venom 70% Chance to Shrug off all debuffs
Karnak 65% reduced poison damage.
Reduced duration for Non-damaging debuffs Depending on Signature
Corvus Glaive Bleed + Coldsnap + Shock (When Immunity is active)
King Groot Shrug off debuffs after 0.5 sec at the cost of 1 fury buff
Groot 55% Reduced Duration for all Debuffs
Ghost with Hood Synergy Takes no damage while phasing
Iron Man Infinity War Bleed + Coldsnap(when Armor’s Up)
Mysterio “Mind Control (Reverse Control) Immunity WithEmma Frost Synergy.
Ability Accuracy Immunity (Shuts down for 10 secs if armor is broken or not Knocked Out by Spider-Verse Champs).”
Nebula Can shrug off 3 Shockdebuffs and gain 5 shock charges each
Captain America IW with Skill Champ Synergy up to 100% chance to purify all debuffs at the cost of 1 kinetic potential (Depends on the amount of added signature)
Gladiator Hulk Regenerates 70% of damage taken by debuffs.
She-Hulk (Duped) X% chance to purify Debuff Each Hit She lands against Science champs
Wasp 8% to shrug off debuffs (except bleed) and evade
Red Hulk Shrug off Incinerate and poison debuffs and convert into heat rage
All Champions with Nick Fury and Deadpool (all versions) Synergy If Nick Fury is alive, Once per-fight all team members (except Nick Fury) can purify poison, shock, and bleed debuff and regenerate 10% of max health. Perfect for debuff nodes.
Conditional Immunity (2)

“No” champion is immune to Magik’s Limbo and Void’s Intimidating Presence Debuffs. But some champions can avoid this.

Champions
Immunity
Archangel Void is not likely to apply any Intimidating Presence Debuffs and Magik won’t trigger Limbo afterArchangel put Neuro debuffon them.
Domino Makes the Void’s Debuff and Magik’s limbo fail now and then.
Blade with Ghost Rider Synergy There is 85% chance that Blade will prevent passive debuffs (e.g. Void’s Intimidation debuffs and Magik’s Limbo)
Nick Fury (Duped) Stun Immunewhen he is knocked out once and his life model decoy is destroyed
Captain Marvel Takes no damage when indestructible is active
Quake You got to apply Concussion Debuff on Void to prevent intimidating debuff and So will it prevent Magik’s Limbo. It may not be possible when Void/Magik is placed on Stun Immune Node
She-Hulk (Duped) X% chance to purify Debuff Each Hit She lands against Science champs
Luke Cage Takes no damage when indestructible is active
All Champion withShrug off orReduced PotencyFeature (Not Applicable for Magik’s Limbo) All the champions that can shrug off debuffs are good against Void. Check the Shrug Off List Above
Any Champion With Pacify Mastery When you parry Magik and attack her she is 30% less likely to get limbo if she fills power bar.
Note: Useless on Limber and Stun-Immune Node